Summary

  • Patients often present with recurrent pulmonary infections, including a chronic daily productive cough with mucopurulent sputum production.
  • Diagnostic testing for a potential etiology of unexplained bronchiectasis should be performed.
  • A sputum sample should be obtained during acute exacerbations and systemic antibiotics directed toward prior culture results should be administered.
  • Daily airway clearance is essential for treatment success.
  • Maintenance aerosolized antibiotics should be used for treatment of severe bronchiectasis or recurrent Pseudomonas aeruginosa infections.
  • Surgical therapy, including lung transplantation, should be considered for patients who continue to deteriorate despite optimal medical management.

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